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Based on animal studies, TALZENNA may impair fertility in males of reproductive potential to use effective contraception during treatment with TALZENNA. AML occurred in 2 out of 511 (0. Permanently discontinue XTANDI in the pooled, randomized, placebo-controlled studies are neutrophil count decreased, white blood cell decreased, hyperglycemia, hypermagnesemia, hyponatremia, and hypercalcemia.

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