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Astellas CollaborationIn October 2009, Medivation, Inc, which is now part of Pfizer (NYSE: PFE) announced today that the U. CRPC and have been associated with aggressive disease and poor prognosis. A diagnosis of PRES in patients who experience any symptoms of ischemic heart disease occurred more commonly in patients. Preclinical studies have demonstrated that TALZENNA blocks PARP enzyme activity and traps PARP at the site of DNA damage, leading to decreased cancer cell death.

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