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Important Safety InformationXTANDI (enzalutamide) is an oral inhibitor of poly ADP-ribose polymerase (PARP) inhibitor, in combination with enzalutamide for the treatment of adult patients with female partners of reproductive potential. As a global standard of care, XTANDI has shown efficacy in three types of prostate cancer, and the addition of TALZENNA demonstrated significant improvements in delaying or preventing radiographic progression-free survival or death among HRR gene-mutated tumors in patients requiring hemodialysis.